Genetics of Radiosensitivity:
Jen KY., Cheung VG.: Transcriptional response of lymphoblastoid cells to ionizing radiation. Genome Research 13:2092-2100, 2003.
Correa CR., Cheung VG.: Genetic variation in radiation induced expression phenotypes. Amer J Hum Genet 75: 885-890, 2004.
Jen KY., Cheung VG.: Identification of p53 target genes involved in ionizing radiation stress response. Cancer Research 65:7666-7673, 2005.
Smirnov DA., Morley M., Shin E., Spielman RS. & Cheung VG.: Genetic analysis of radiation-induced changes in human gene expression. Nature [Epub ahead of print], 2009.
Genetics of Human Gene Expression:
Cheung VG. , & Spielman RS.: The genetics of variation in gene expression. Nature Genetics 32: 522-525, 2002.
Cheung VG., Conlin LK., Weber TM., Arcaro M., Jen KY., Morley M., Spielman RS.: Natural variation in human gene expression assessed in lymphoblastoid cells. Nature Genetics 33: 422-425, 2003.
Cheung VG., Jen KY., Weber TM., Morley M., Devlin JL., Ewens KG., Spielman RS.: Genetics of quantitative variation in human gene expression. Cold Spring Harbor Symposia on Quantitative Biology Vol 68 th: 403-407, 2003.
Morley M., Molony CM., Weber T., Devlin JL., Ewens KG., Spielman RS., Cheung VG.: Genetic analysis of genome-wide variation in human gene expression. Nature 430: 743-747, 2004.
Spielman RS., Bastone LA., Burdick JT., Morley M., Ewens WJ. & Cheung VG.: Common genetic variants account for differences in gene expression among ethnic groups. Nature Genetics 39: 226-231, 2007.
Wang X., Tomoso DJ., Chorley BN., Cho HY., Cheung VG., Kleeberger SR. & Bell DA.: Identification of polymorphic antioxident response elements in the human genome. Human Molecular Genetics 16: 1188-1200, 2007.
Cheung VG., Bruzel A., Morley M., Devlin JL., Spielman RS.: Monozygotic twins reveal germline contribution to allelic expression differences. Am J Hum Genet 82: 1357-60, 2008.
Price AL., Patterson N., Hancks DC., Myers S., Reich D., Cheung VG., Spielman RS.: Effects of cis and trans genetic ancestry on gene expression in African Americans. PLoS Genet 4: e1000294, Epub 2008.
Cheung VG. & Spielman RS.: Genetics of human gene expression: mapping DNA variants that influence gene expression. Nat Rev Genet 10(9):595-604, 2009.
Nayak RR., Kearns M., Spielman RS. & Cheung VG.: Coexpression network based on natural variation in human gene expression reveals gene interactions and functions. Genome Res [Epub ahead of print], 2009.
Meiotic Recombination:
Cheung VG., Burdick JT., Hirschmann D. & Morley M.: Polymorphic variation in human meiotic recombination. Amer. J. Hum. Genet 80: 526-530, 2007.
Chowdhury R., Bois PR., Feingold E., Sherman SL. & Cheung VG.: Genetic analysis of variation in human meiotic recombination. PLoS Genet 5(9):e1000648, Epub 2009.
Genotype Inference Method:
Burdick JT., Chen WM., Abecasis GR., Cheung VG.: In silico method for inferring genotypes in pedigrees. Nature Genetics 38(9): 1002-1004, 2006.
Direct IBD Mapping:
Cheung VG., Nelson SF.: Genomic mismatch scanning identifies human genomic DNA shared identical by descent. Genomics 47(1): 1-6, 1998.
Grant GR., Manduchi E., Cheung VG., Ewens WJ.: Significance testing for direct identity-by-descent mapping. Annals of Human Genetics 63(Pt 5): 441-454, 1999.
Smirnov D., Bruzel A., Morley M., Cheung VG.: Direct IBD Mapping: An Identical-by-Descent Mapping Method Without Genotyping. Genomics 83: 335-345, 2004.
Bruzel A., Cheung VG.: DNA Reassociation using oscillating phenol emulsions. Genomics 87(2): 286-289, 2006.
BAC Map of the Human Genome & GenMapDB:
Cheung VG., Morley M., Aguilar F., Massimi A., Kucherlapati R., Childs G.: Making and reading microarrays. Nature Genetics 21: 15-19, 1999.
Cheung VG., Dalrymple HL., Narasimhan S., Watts J., Schuler G., Raap AK., Morley M., Bruzel A.: A resource of mapped human bacterial artificial chromosome clones. Genome Research 9(10): 989-993, 1999.
Morley M., Arcaro M., Burdick J., Yonescu R., Reid T., Kirsch IR., Cheung VG.: GenMapDB: a database of mapped human BAC clones. Nucleic Acids Research 29(1): 144-147, 2001.
The International Human Genome Mapping Consortium.: A physical map of the human genome. Nature 409: 934-941, 2001.
Cheung VG., Nowak N., Jan W., et al.: Integration of cytogenetic landmarks into the draft sequence of the human genome. Nature: 953-958, 2001.
Smirnov D., Burdick JT., Morley M., Cheung VG.: Method for manufacturing whole genome microarrays by rolling circle amplification. Genes, Chromosomes & Cancer, 40: 72-77, 2004.
Phenotype of Carriers of Autosomal Recessive Diseases:
Watts JA., Morley M., Burdick JT., Fiori JL., Ewens WJ., Spielman RS., Cheung VG.: Gene expression phenotype in heterozygous carriers of ataxia telangiectasia. Amer J Hum Genet 71: 791-800, 2002.
Cheung VG., Ewens WJ.: Heterozygous carriers of Nijmegen Breakage Syndrome have a distinct gene expression phenotype. Genome Research, 16(8): 973-979, 2006.
Smirnov DA., Cheung VG.: ATM gene mutations result in both recessive and dominant expression phenotypes of genes and microRNAs. Am J Hum Genet 83: 243-53, 2008.
